1988 Journal article Legacy File

Causes of venous ulceration: a new hypothesis

Primary Investigators / Authors

P D Coleridge Smith | P Thomas | J H Scurr

Document Abstract / Summary Overview

Previous hypotheses about the causes of venous ulceration are inconsistent with recently published data. In patients with chronic venous insufficiency the number of functioning capillary loops visible in the skin on microscopy fell after the legs had been dependent for 30 minutes. Another study had shown that leucocytes became trapped in the circulation in dependent legs. A new hypothesis linking these two findings proposes that the trapped while cells occlude the capillaries and result in ischaemia of the skin of the leg.

Resource Access Nodes

British Medical Journal (Clinical Research Edition) 6/18/1988, Vol. 296 Issue 6638, p1726 →

Technical Properties

Accession ID: ISSN: 0267-0623

Archival Collection: UKZN-IKS

Language Registry: English

Asset Extent / Duration: 2 Pages

Publisher: BMJ Publishing Group

Rights Management Attribution: BMJ

Licence Data: Creative Commons Public Domain Mark 1.0

Co-Authors & Contributors

P D Coleridge Smith | P Thomas | J H Scurr creator

Taxonomy Classifications

🏷️ UKZN-IKS 🏷️ United Kingdom

Subject Keywords

# Chronic Disease , Humans , Ischemia , Leukocytes , Regional Blood Flow , Varicose Ulcer , skin

Geographic Spatial Coverage

📍 United Kingdom

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